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The Food and Drug Administration, FDA, has approved the drug Vivitrol to the treatment of opioid dependence according to a news release by them on 10-12-2010.

Using two separate drugs to shed weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you ought to err to the side of caution and let the FDA do its job and demand some research be done in order that the public knows the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to generate money and that they would say everything to keep people on his or her medications.

Researchers found that participants using this drug for any year, lost excess weight within four weeks and have kept the load off throughout the 56 weeks in the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which might be made up of multiple active ingredient, that might make them more efficient and safer.

Combo-pilling is the newest fad or in addition to this the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is now popular is the fact that since right now there are no long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug may also raise blood pressure levels and heartrate, and shouldn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise hypertension and heartbeat and must not used in patients with uncontrolled high blood pressure levels, in addition to by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients using a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients on the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.


The most common effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.